Hamlin won at his home track for the first time, while Busch finished fifth. But it wasnt enough as Brian Vickers finished seventh to claim the 12th and final spot the Chase.
Busch, despite four victories this season, fell eight points short of making the Chase. Its the smallest margin since the format began in 2004.
Matt Kenseth started the race holding down the final qualifying spot, but had an awful night and finished 25th to drop out of contention.