Chris Osgood made 37 saves for the defending Stanley Cup champions. Game 3 is Friday night in Chicago.
Jonathan Toews' second goal of the game with 7:40 to go in regulation pulled Chicago into a 2-2 tie.
Toews gave Chicago the lead midway through the first period, but Brian Rafalski got Detroit even later in the frame. Dan Cleary made it 2-1 early in the second.
Nikolai Khabibulin stopped 35 shots for the Blackhawks.