The pick was the first for new coach Josh McDaniels and rookie general manager Brian Xanders, who replaced Mike Shanahan after 14 seasons in charge at Dove Valley.
The Broncos took Tennessee linebacker Robert Ayers with the 18th pick. The have plenty of needs on defense as they transition to a 3-4 scheme, but the 33-year-old McDaniels needs upgrades on offense, too.
Denver signed three running backs in free agency J.J. Arrington, LaMont Jordan and Correll Buckhalter to compete with holdovers Peyton Hillis, Selvin Young and Ryan Torain.
It was a big day for former Bulldogs. Quarterback Matthew Stafford was taken by the Detroit Lions with the top pick in the draft.