The win gives the Crimson Tide (8-0, 5-0 Southeastern Conference) its first back-to-back wins over the Volunteers (3-5, 1-4) in a usually streaky "Third Saturday in October" series since the 1991-92 seasons.
While the Tide remained in the heart of the national championship race, Tennessee's season grew sorrier. A lopsided loss to a bitter rival will only increase the pressure on coach Phillip Fulmer, who has been a prime target for critics and disgruntled Vols fans.
NO. 5 FLORIDA 63, KENTUCKY 5
In Gainesville, Fla., Tim Tebow threw two touchdown passes and ran for two scores to help the Gators (6-1, 4-1) extend their winning streak in the series to 22 games.
The Gators showed no signs of sluggishness coming off a bye and didn't have a letdown following a 51-21 drubbing of defending national champion LSU two weeks ago.
The Gators blocked punts on Kentucky's first two possessions and turned them into short touchdown runs, and led 28-0 before the Wildcats (5-3, 1-3) even got a first down.
MISSISSIPPI 23, ARKANSAS 21
In Fayetteville, Ark., Jevan Snead threw two touchdown passes, and Mississippi held off an Arkansas rally to give coach Houston Nutt a win over his former team.
The Rebels (4-4, 2-3) led 23-14 with 1:45 remaining, but Arkansas quickly cut the deficit to two on Casey Dick's 22-yard touchdown pass to Greg Childs. The Razorbacks (3-5, 1-4) then recovered an onside kick, but Ole Miss didn't threaten.
Nutt coached the Hogs for 10 seasons before leaving after last season to take over at SEC West rival Ole Miss.
DUKE 10, VANDERBILT 7
In Nashville, Tenn., Nick Maggio kicked a 42-yard field goal in the third quarter after Duke missed its first two attempts, and the Blue Devils held on to snap a six-game skid in the non-conference series.
Duke (4-3) put a serious dent in Vanderbilt's bowl hopes. The Commodores (5-3) lost their third game in a row in trying to become bowl eligible for the first time since 1982.
MISSISSIPPI ST. 31, MIDDLE TENNESSEE ST. 22
In Starkville, Miss., Anthony Dixon rushed for 124 yards and three touchdowns to lead the Bulldogs (3-5). who rushed for 168 yards, their second highest total of the season.
The Blue Raiders (2-6) dropped to 0-3 against Mississippi State. Middle Tennessee is 3-16 against SEC teams.