Jaybo Shaw, who played all but eight snaps of Georgia Tech's 38-7 win over Mississippi State on Sept. 20, could make his first start when the Yellow Jackets play Duke.
Starter Josh Nesbitt was held out of practice Tuesday after suffering a strained right hamstring against Mississippi State. Nesbitt was injured on the Yellow Jackets' opening drive and sat out the rest of the game as Shaw led a dominant offensive performance.
An off week has given Nesbitt extra time to recover, but Shaw worked with the first-team offense Tuesday.
Nesbitt also missed practice Monday and wasn't available for comment on Tuesday.
"It's like day-to-day," coach Paul Johnson said about Nesbitt's status.
"Right now it's too hard to call. We're practicing the other guys. If Josh doesn't play, he doesn't play. It won't surprise me. If he is able to come in and play it might not surprise me either.
"We don't dwell on that. We just get ready with the guys who are playing."
Shaw said he is preparing to start.
"I've just got to get myself prepared, and I think I'm doing as much as I can to be the starter on Saturday," Shaw said.
"I want to go out and just try to lead the team. I don't have to do anything spectacular, just lead the offense, don't turn the ball over, just lead the team like we did against Mississippi State."
Johnson said Nesbitt "tried to run a little bit" Monday but couldn't participate in drills.
Georgia Tech (3-1 overall, 1-1 ACC) will be playing its first home conference game after winning at Boston College and losing at Virginia Tech. Duke (3-1, 1-0) is coming off a 31-3 win over Virginia that ended its 25-game losing streak in conference games.
Georgia Tech will be favored against Gardner-Webb next week and, if it beats Duke, could be 5-1 when Clemson visits on Oct. 18.
Johnson cringed at the suggestion he might talk with his players about the opportunity ahead.
"My big picture is the Duke game," Johnson said. "That's the only picture they need to worry about right now. You better take care of your business.
"It's a conference game and it's a team that's 3-1 and that's more than enough for us to worry about. You start looking ahead, you'll be looking back in misery. All our focus is on Duke."