Michael Kelly Fields, 40, died at 2:14 a.m. at Joseph M. Still Burn Center at Doctors Hospital, a spokeswoman said.
Family members and others in the center's waiting area said Mr. Fields was injured after he re-entered the burning refinery to help co-workers trapped inside, said center spokeswoman Beth Frits.
Mr. Fields worked as a forklift operator for a contractor hired by the sugar company, according to his brother-in-law, Glenn Burnsed.
Fourteen patients from the explosion remain in critical condition, and two are in serious condition, according to a hospital statement.
Reach Adam Folk at (706) 823-3339 or firstname.lastname@example.org.