Holmes, the tournament winner as a rookie two years ago, shot 6-under 65 to share the lead with Doug LaBelle II at 9-under 133 among players who finished the second round Friday. LaBelle shot a 64.
A 90-minute frost delay to start the day left 45 golfers on the course when play was halted because of darkness.
One of them, Camilo Villegas, was tied for the lead at 9 under through 12 holes. Two were at 8 under on the course -- Bill Haas through 13 holes and Ben Crane through 14.
They'll complete the round today before the cut is made, then the third round will begin.
Pat Perez and Nick O'Hern shot 65s and were one behind the leaders at 8 under. Augusta native Charles Howell, Stuart Appleby, Briny Baird and Robert Allenby were 7 under.
Two-time champion Phil Mickelson had four birdies, but three-putted from 7 feet for a double bogey on the par-4, 464-yard ninth hole. Mickelson was 5 under, four shots off the lead, through 14 holes.
Vaughn Taylor finished they day at even par, following up his opening round of 72 with 70 Friday. He likely will miss the cut when it is determined today.
NATIONWIDE TOUR: In Morelia, Mexico, Greg Chalmers shot 6-under-par 65 and holds a two stroke lead after two rounds of the Mexico Open.
Chalmers is at 9-under 133 for the tournament at Tres Marias Golf Club. He is one stroke better than rookie Matt Every (65) and two ahead of first-day leader Tom Johnson (70).
Augusta's Scott Parel shot 75-76--151 and missed the cut.
WOMEN'S AUSTRALIAN OPEN: In Melbourne, Australia, amateur Kristie Smith shot 4-under 69 for a two-stroke lead over South Korea's Shin Ji-yai and was three ahead of defending champion Karrie Webb after the second round.
The 19-year-old Smith was at 5-under after two rounds at the Kingston Heath course.