Shan Foster added 20 points, and Alan Metcalfe scored 14 for Vanderbilt (13-0), which won its first 12 games in 2003-04 and advanced to the regional semifinals in the NCAA tournament.
Vanderbilt is one of six unbeaten Division I teams. North Carolina, Memphis, Kansas, Washington State and Mississippi are the others.
Gary Springer led Iona (5-9) with 17 points, and Devon Clarke added 15 points for the Gaels.
NO. 7 GEORGETOWN 82, FORDHAM 55
In Washington, DaJuan Summers had 15 points and nine rebounds, Jonathan Wallace scored 19, and Georgetown closed out its nonconference schedule with a victory against Fordham.
Austin Freeman had 12 points, and Jessie Sapp and Roy Hibbert added 11 for the Hoyas (10-1).
NO. 12 TEXAS A&M 68, RICE 41
In College Station, Texas, Josh Carter and DeAndre Jordan scored 16 points apiece, and Texas A&M beat Rice for its sixth consecutive win.
Jordan, a 7-foot freshman, also had 12 rebounds and four blocks.
The Aggies (13-1) led 33-18 at halftime.
NO. 1 CONNECTICUT 82, ARMY 33
In Hartford, Conn., Mel Thomas scored 19 points and showed off her long-range game, as Connecticut routed Army.
Thomas hit her first seven shots, including five 3-pointers, and the Huskies (11-0) put away the Black Knights (6-6) early.
Connecticut opened the game with a 17-3 run and led 47-15 at the break.