Coach John Fox on Friday named 43-year-old Vinny Testaverde the starting quarterback for Sunday's game against Indianapolis. Testaverde got the nod ahead of David Carr, who is recovering from a back injury.
"It's not an indictment on David Carr by any stretch. I don't feel he's 100 percent," Fox said. "He's healthy enough to play, but I don't think he's 100 percent."
Carr practiced Friday and is listed as probable.
The surprising move pits Testaverde, in his 21st season, against reigning Super Bowl MVP Peyton Manning as the Panthers try to become the first team to beat the Super Bowl champions this season.
EAGLES: Sarting right tackle Jon Runyan missed his third consecutive practice Friday and is questionable to make his 185th consecutive start Sunday against the Vikings.
Runyan bruised his tailbone in a training room fall last week, but played in Philadelphia's 19-16 loss to Chicago. He sat out practice this week and will be re-evaluated once the team arrives in Minnesota.
"We have a long flight up there. We'll keep giving him treatment, and so on, to see how he does," coach Andy Reid said.
The Eagles (2-4) also could be without both of their starting safeties.
All-Pro Brian Dawkins, who hasn't played since sustaining a neck stinger in Week 2, is doubtful, though he practiced the past two days.
Safety Sean Considine hurt his ankle in practice Thursday but returned to the field Friday and is also questionable.
VIKINGS: Won't announce a starting quarterback until Sunday morning, but signs still point to veteran Kelly Holcomb replacing the injured Tarvaris Jackson against Philadelphia.
Jackson was listed as questionable on Friday's injury report with a broken index finger on his throwing hand. Coach Brad Childress said Jackson will either start or be the emergency third quarterback against the Eagles, in which case Holcomb would be the starter.
JAGUARS: Running back Maurice Jones-Drew was limited in practice Friday - the third consecutive day he's missed part of team drills - and was listed as questionable against Tampa Bay.
JETS: Linebacker Jonathan Vilma will miss New York's game against Buffalo on Sunday with a knee injury.