Playing for the first time in three weeks, Cassell scored 10 points during the Clippers' decisive 17-3 fourth-quarter surge, including a 3-pointer that gave Los Angeles the lead for good at 79-77 with 9:12 to play. He sandwiched another 3-pointer between two jumpers, and Mobley added a jumper for a 91-80 Clippers lead.
Cassell had missed seven games with plantar fasciitis in his left heel before returning against the Hornets, and Mobley hyper extended his left elbow last week at Miami.
They showed no mercy against the Hornets, who are without injured starters Chris Paul (sprained ankle), Peja Stojakovic (back surgery) and David West (right elbow surgery).
Desmond Mason led New Orleans with 28 points for the second consecutive game.