PITTSBURGH -- The Florida Marlins lost their 10th straight game on Saturday when pinch-hitter Jose Guillen homered on Jay Powell's first pitch in the 10th inning, giving the Pittsburgh Pirates a 7-6 win.
Florida hasn't won since beating Chicago in the season opener on March 31, and are off to the worst start ever by a World Series champion.
The 1947 Cardinals, 1964 Dodgers and 1984 Orioles started their seasons 2-8.
After retiring the Pirates in the ninth, Powell (0-2) surrendered Guillen's third home run in his first pinch-hitting appearance this season.
Rich Loiselle (1-0) got the win despite allowing blowing his second save in the ninth when Craig Counsell's RBI groundout tied it 6-6. The Marlins blew a chance to take the lead when Mark Kotsay grounded out and Derrek Lee struck out with the bases loaded.
Kevin Young hit a two-run homer off Livan Hernandez in the first inning and drove in four for the Pirates. He has a career-high 10-game hitting streak.
Pittsburgh starter Francisco Cordova allowed four runs, three earned, and five hits in 5 1-3 innings. He gave up two runs in the first, doubling his season total in 14 innings.