Coach Gary Kubiak said Williams will go on injured reserve and undergo surgery in the next week.
Williams appeared to be hurt while sacking Jason Campbell with about five minutes left in the first quarter.
Williams, the top overall pick in the 2006 draft, moved from defensive end to outside linebacker this season in new coordinator Wade Phillips’ 3-4 alignment. He was growing more comfortable with the role each week, and had five sacks and a forced fumble before the injury.
FALCONS: Atlanta is hoping defensive end John Abraham and center Todd McClure will be able to play Sunday against Carolina.
Abraham (hip) and McClure (knee) did not dress for Atlanta’s loss to Green Bay. Falcons’ coach Mike Smith wouldn’t address injuries that knocked receiver Julio Jones, safety William Moore and nickel back Christopher Owens out of the game.
Moore (shoulder) and Owens (head) left in the first half and didn’t return, while Jones left in the fourth quarter with a hamstring injury.
BRONCOS: John Fox is going to wait a day to announce his starting quarterback.
The coach gave his players the day off Monday and didn’t want to let everyone else know before Tim Tebow or Kyle Orton finds out.
Tebow replaced Orton and energized the Broncos and their fans before coming up short in a 29-24 loss to San Diego on Sunday.
SEAHAWKS: Quarterback Tarvaris Jackson has a “high-grade” strained right pectoral muscle he injured in a win over the Giants and will be rested during the Seahawks’ bye week.
Coach Pete Carroll said that Jackson had an MRI that “showed some stuff” in the chest area and there is no time frame for how long Jackson might be out.
PACKERS: Coach Mike McCarthy says offensive lineman Chad Clifton has a “significant” hamstring injury, which occurred during Sunday night’s win over Atlanta.
McCarthy said it might be “a couple of weeks” before the team knows the severity of the injury.
BROWNS: Defensive lineman Marcus Benard was been injured in a motorcycle accident after practice.
Team spokesman Neal Gulkis said Benard was in stable condition after the accident, which happened near Interstate 71 shortly after Benard left the team’s training facility.
The team does not know the extent of Benard’s injuries or his condition.