Kurt Busch won at Charlotte Motor Speedway, giving Penske his first win in the 600.
Busch led 232 of the first 340 laps, but his car started a slow fade as Jamie McMurray started a charge that could have given owner Chip Ganassi a historic sweep of the Indy-car and stock car doubleheader. Dario Franchitti won the Indy 500 for Ganassi's team earlier in the day.
"It's unbelievable how much this is a team effort," Kurt Busch said. "McMurray kept us honest, I'll give him that. It's amazing when things click."
A week ago Busch made Penske a winner at the Sprint All-Star race at Charlotte. On Sunday he made him a winner in one of the biggest regular season races of the NASCAR season.
It wasn't Indy, but it wasn't bad.
"My old buddy Penske beat me tonight," Ganassi said.
"Roger this is for you," Busch said. "I saw that Ganassi car coming up from behind me and he wasn't going to get by us."
Kyle Busch rebounded from early troubles to finish third.