Seguin hesitated as he drove in on Carey Price before firing a shot past the goalie.
David Krejci sent a shot off the post on Boston’s first attempt.
Tim Thomas stopped Rene Bourque, Max Pacioretty and Lars Eller for his 24th win. He made 26 saves during regulation and overtime.
Andrew Ference, Benoit Pouliot and Patrice Bergeron scored for Boston, which began a six-game trip – its longest of the season – on a winning note following a 2-4 skid.
DUCKS 2, PENGUINS 1
In Pittsburgh, Teemu Selanne beat goalie Marc-Andre Fleury midway through the third period, and Anaheim snapped Pittsburgh’s six-game, home-winning streak.
Corey Perry added his 28th goal, and Jonas Hiller made 25 saves for Anaheim, which won in Pittsburgh for the first time in 11 years by slowing down Penguins star Evgeni Malkin.
The NHL’s leading scorer was held pointless for the second time this month, and his eight-game goal streak at home ended, too.
Jordan Staal scored for Pittsburgh, but the Penguins’ high-flying offense was bottled up over the last two periods.
SENATORS 6, PANTHERS 2
In Sunrise, Fla., Craig Anderson made 42 saves, six Ottawa players scored, and the Senators routed the Panthers for their ninth consecutive win against Florida.
Jim O’Brien notched his first career goal, Milan Michalek moved into a tie for the team lead with his 25th of the season, and Kaspars Daugavins, Bobby Butler, Daniel Alfredsson, and Filip Kuba also scored for the Senators.
Ottawa has beaten the Panthers five straight times in Florida and 17 of 20 on the road.
Shawn Matthias and Brian Campbell scored for the Panthers. Scott Clemmensen allowed four goals on 16 shots before being replaced by Jose Theodore with 5:54 left in the second.
Theodore, who hadn’t played since Jan. 20, stopped 13 of 15 shots.