Goalie Mike Smith won his fourth consecutive start for Tampa Bay, a winner of seven in a row against the Thrashers and two of three overall.
Atlanta goalie Chris Mason was pulled after giving up three goals in the first period, giving way to Peter Mannino, who stopped 15 of 16 shots in the final two periods.
SENATORS 4, SABRES 2
In Buffalo, N.Y., Daniel Alfredsson had his eighth career hat trick and reached 1,000 NHL points, and Brian Elliott made 34 saves in Ottawa's victory.
Elliott improved to 9-0-0 against the Sabres.
BLUES 4, BLACKHAWKS 2
In St. Louis, Roman Polak broke a third-period tie, and David Perron scored twice to help St. Louis beat Stanley Cup champion Chicago.
FLAMES 6, BLUE JACKETS 2
In Columbus, Ohio, Rene Bourque scored three goals and added an assist and Henrik Karlsson stopped 20 shots in his NHL debut to lead Calgary past Columbus.
It was Bourque's second career hat trick.
SUSPENDED: Enforcer Rick Rypien was suspended six games Friday for grabbing a fan during Vancouver's loss to Minnesota on Tuesday.
The Canucks also were fined $25,000, as required by NHL policy.