Ben Turner threw for a touchdown and rushed for another to led the Red Devils (10-1).
The teams had closed out the regular season on Nov. 9, with Lincoln County winning that one 27-8.
After a week off to determine the playoff bracket, they squared off again on Friday night with a similar result.
Turner hit Zireycus Letman on a 7-yard TD pass in the third quarter to make it 14-0, then scored on a 3-yard run in the fourth quarter.
Mike McIntyre scored the Red Devils’ first touchdown on a 1-yard run in the second quarter.
The Red Devils will be at home again Friday for the second round.
Hancock Cent. 0 0 0 0 – 0
Lincoln Co. 0 7 7 7 – 21
L–Mike McIntyre 1 run (James Spratlin kick), 10:43
L–Zireycus Letman 7 pass from Ben Turner (Spratlin kick), 4:49
L–Turner 3 run (Spratlin kick), 3:45
Record: Lincoln County 10-1.