Kuchar, who started the day one shot off Kevin Na's lead, closed with 2-under-par 70 to win by two shots. He finished at 13-under 275 for his fourth career victory.
Among other perks, the victory earns Kuchar a three-year exemption into the Masters Tournament. He already had qualified for the 2013 Masters by virtue of his top-16 finish last month.
Kuchar, who had a share of the lead at Augusta National after 15 holes, tied for third place.Four players - Martin Laird (67), Zach Johnson (68), Ben Curtis (68) and Rickie Fowler (70) - tied for second place behind Kuchar at The Players Championship.