Jalen Saunders added six catches for 153 yards receiving and both of Bell’s touchdown passes for the Sooners (7-1, 4-1 Big 12 Conference), who rallied after falling behind in the third quarter.
Williams finished with 97 yards rushing for Oklahoma, which forced three turnovers by the Red Raiders.
The loss was the first of the season for Texas Tech (7-1, 4-1) and first-year coach Kliff Kingsbury.
Davis Webb finished 33 of 52 passing for 385 yards for the Red Raiders, who were led by Jace Amaro’s 119 yards receiving on eight catches. Eric Ward added nine catches for 106 yards.
NO. 4 OHIO STATE 63, PENN STATE 14
In Columbus, Ohio, Braxton Miller passed for three touchdowns and ran for two and Carlos Hyde rushed for 147 yards and two more scores to lead Ohio State to a victory over Penn State.
It was the most points surrendered by Penn State (4-3, 1-2 Big Ten) and its worst beating in 114 years.
The Ohio State (8-0, 4-0) victory stretched the nation’s best winning streak to 20 in a row, two behind the school mark which included the 1968 national championship season.
That team was recognized during the opening half as the Buckeyes streaked to a 42-7 lead.
NO. 6 BAYLOR 59, KANSAS 14
In Lawrence, Kan., Bryce Petty threw for 430 yards and three touchdowns in fewer than three quarters, Lache Seastrunk ran for 109 yards and a score and Baylor (7-0, 4-0) routed Kansas (2-5, 0-4) in a Big 12 game for its school-record 11th consecutive win.
The Bears piled up 500 yards of offense in taking a 38-0 lead by halftime, and then relaxed as coach Art Briles pulled many of his starters in the third quarter.
The nation’s highest-scoring offense still finished with 743 yards, and eight of its nine scoring drives took fewer than 2 minutes.
NO. 18 LOUISVILLE 34, SOUTH FLORIDA 3
In Tampa, Fla., Teddy Bridgewater threw for 344 yards and three touchdowns and Louisville (7-1, 3-1) crebounded from its first loss of the season with a rout of South Florida in an American Athletic Conference game.
Bridgewater completed 25 of 29 passes with no interceptions, hiking his totals for the season to 23 touchdowns with two picks.
Charles Gaines returned a fourth-quarter interception 70 yards for a touchdown and the Cardinals outgained the Bulls (2-5, 2-1) 485 yards to 133.
NO. 19 OKLAHOMA STATE 58, IOWA STATE 27
In Ames, Iowa, Desmond Roland ran for a career-high 219 yards and four touchdowns and Oklahoma State (6-1, 3-1) routed Iowa State (1-6, 0-4) in a Big 12 game for its third consecutive win.
Quarterback Clint Chelf had 163 total yards in his second start of the season for the Cowboys (6-1, 3-1 Big 12), who ran for a season-high 342 yards.
Oklahoma State scored 14 points in a 2-½ minute stretch late in the third quarter to extend its lead to 45-20.
NO. 21 CENTRAL FLORIDA 62, CONNECTICUT 17
In Orlando, Fla., Blake Bortles threw for four touchdowns and ran for another as Central Florida (6-1, 3-0) routed Connecticut (0-7, 0-3) in an American Athletic Conference game.
Bortles completed his first eight passes and ended his day early in the third quarter, connecting on 20 of 24 for 286 yards.
Connecticut has lost eight consecutive games dating to last season.
NO. 23 NORTHERN ILLINOIS 59, EASTERN MICHIGAN 20
In De Kalb, Ill., Jordan Lynch threw four touchdown passes and caught another as Northern Illinois reached its best start as a major college football program.
The Huskies (8-0, 4-0 Mid-American Conference) never trailed on the way to a season-high in points and second-highest total offense (606 yards).
The Eagles (1-7, 0-4) lost their seventh in a row.
MINNESOTA 34, NO. 25 NEBRASKA 23
In Minneapolis, Philip Nelson rushed for two touchdowns and passed for another, guiding Minnesota (6-2, 2-2) to an upset of Nebraska (5-2, 2-1), the first win by the Gophers since 1960 against the Cornhuskers, in a Big Ten game.
Nelson made all of his seven completions count, totaling 152 yards, and carried the ball eight times for 55 yards. He spun across the goal line from the 1 with 48 seconds left to seal the victory for the Gophers, who became bowl-game eligible and stopped a 16-game losing streak to the Huskers.
Taylor Martinez returned from a turf-toe injury that kept him of the last three games for the Huskers, but he had only 16 yards rushing on eight attempts and 139 yards on 16 for 30 passing, plus one touchdown and one interception.
David Cobb gained 138 yards for the Gophers, who outgained the Huskers 271-189 on the ground.