The Ducks (2-0), who gained a school-record 772 yards last week in beating Nicholls State, looked capable of doing it again against a Virginia defense that hoped to keep the Cavaliers in the game. Oregon finished with 557 yards and did all its scoring while possessing the ball for just 21:25.
Virginia got a very early look at what it was up against as Mariota dropped back on a third-and-5 in the game’s opening series, then bolted up the middle untouched, going 71 yards for a touchdown.
Mariota finished with 122 yards rushing on four carries and completed 14 of 28 passes for 199 yards.
NO. 19 NORTHWESTERN 48, SYRACUSE 27
In Evanston, Ill., Trevor Siemian threw for 259 yards and a career-high three touchdowns, Kain Colter passed for a touchdown and ran for one, and Northwestern pounded Syracuse.
Tony Jones added a personal-best 185 yards receiving and a 47-yard TD, and the Wildcats (2-0) racked up 581 yards in all. They also intercepted Syracuse’s Drew Allen four times on the way to an easy victory.
VIRGINIA TECH 45, WESTERN CAROLINA 3
In Blacksburg, Va., Trey Edmunds ran for two touchdowns and Detrick Bonner returned one of his two interceptions for a score as Virginia Tech rebounded from a season-opening loss to top-ranked Alabama by beating Western Carolina.
NORTH CAROLINA STATE 23, RICHMOND 21
In Raleigh, N.C., Niklas Sade’s 48-yard field goal with 33 seconds left lifted North Carolina State past Richmond.
Freshman Bryant Shirreffs accounted for two touchdowns and Pete Thomas was 24 of 31 for 237 yards while helping the Wolfpack rally from an 11-point deficit.
Michael Strauss moved the Spiders (1-1) downfield in the final seconds, but his deep heave with no time left was batted down by Hakim Jones just short of the goal line.
NORTH CAROLINA 40, MIDDLE TENNESSEE 20
In Chapel Hill, Romar Morris scored twice to help North Carolina run out to a big lead and beat Middle Tennessee.
Bryn Renner threw for 339 yards and a touchdown for the Tar Heels.
MARYLAND 47, OLD DOMINION 10
In College Park, Md., C.J. Brown threw for two touchdowns and ran for two, Brandon Ross rushed for 149 yards and Maryland capitalized on three interceptions in a rout of Old Dominion.
DUKE 28, MEMPHIS 14
In Memphis, Tenn., Brandon Connette, subbing for injured starter Anthony Boone, threw for 198 yards and a pair of fourth-quarter touchdowns to lead Duke past Memphis.
The victory marked the first time since 1998 that the Blue Devils have opened the season 2-0.