Manziel was sitting out because of what the school said was an “inadvertent” violation of NCAA rules involving signing autographs.
His first touchdown came on a 23-yard pass to Mike Evans on A&M’s second drive of the half.
Shortly before that, he got into it with a Rice defender, appearing to mimic signing an autograph while getting up from a tackle. He ended his day by getting yanked following an unsportsmanlike conduct penalty for pointing at the scoreboard after a TD pass in the fourth quarter.
“A foolish penalty at the end,” Aggies coach Kevin Sumlin said. “No matter what the comments are or what. He’s going to face that every week with the people chirping. That’s not OK, and obviously I addressed that on the sideline right after the play. That’s something he’s going to have to deal with every week.”
NO. 10 FLORIDA 24, TOLEDO 6
In Gainesville, Fla., Mack Brown had a career day, Jeff Driskel was efficient and Florida opened the season with a victory over Toledo.
Brown ran 25 times for 112 yards and two touchdowns. Driskel completed 17 of 22 passes for 153 yards and a score.
TENNESSEE 45, AUSTIN PEAY 0
In Knoxville, Tenn., Rajion Neal rushed for 141 yards and Justin Worley threw three touchdown passes as Tennessee began Butch Jones’ coaching tenure with a rout of Austin Peay.
ARKANSAS 34, LOUISIANA-LAFAYETTE 14
In Fayetteville, Ark., Brandon Allen was 15 of 22 passing for 230 yards and three touchdowns as Arkansas opened the Bret Bielema era with a win over Louisiana-Lafayette.
WESTERN KENTUCKY 35, KENTUCKY 26
In Nashville, Tenn., Keshawn Simpson ran for a pair of 3-yard touchdowns and Antonio Andrews added his own 3-yard score as Western Kentucky made coach Bobby Petrino a winner in his debut.
AUBURN 31, WASHINGTON STATE 24
In Auburn, Ala., Tre Mason returned a kick 100 yards and Corey Grant scored on a 75-yard run to lead Auburn to a victoryin Gus Malzahn’s debut as the Tigers coach.
MISSOURI 58, MURRAY STATE 14
In Columbia, Mo., James Franklin threw for 318 yards and three touchdowns before coming out early in the third quarter, helping Missouri take command after early struggles and whip Murray State.