Ieasia Walker had nine points for South Carolina (12-2), and her five blocks pushed her over the 200 mark for her career, the 13th Gamecocks player to reach that milestone.
Makensey Campbell and Lindsay Simpson scored nine points apiece for the Catamounts (3-9), who have lost five games in a row.
South Carolina shot 50 percent from the field (28 of 56) and 66.7 percent on 3-pointers (6 of 9). The Gamecocks won the turnover battle with 10 to the Catamounts' 20.
The only suspect statistic from South Carolina was the 4-of-14 shooting from the line.
The Gamecocks led 29-18 at halftime, but with 13:38 left in the second, the advantage was 47-27.
South Carolina's only loss came against No. 1 Stanford, 53-49, on Dec. 19.