The Hawks (2-1) defeated a ranked team for the first time since a victory over No. 15 Auburn on Dec. 29, 2007.
Saint Joseph’s had dropped 10 straight games to the Terrapins before this one but held Maryland scoreless over the final seven minutes.
Alyssa Thomas had 16 points and 15 rebounds while Laurin Mincy added 14 points for the Terrapins (2-1), who opened the season with a 39-point victory over Mount St. Mary’s and a 43-point win over Loyola.
NO. 3 DUKE 84, PRESBYTERIAN 45
In Durham, N.C., Tricia Liston and Haley Peters each scored 21 points, leading Duke to a rout of Presbyterian.
Liston had nine rebounds and four assists and was 4-for-6 from 3-point range.
Chelsea Gray added 12 points for the Blue Devils (1-0), who have appeared in the Elite Eight in each of the past three seasons.
Junior guard Karlee Taylor led Presbyterian (1-2) with a season-high 14 points.
Duke center Elizabeth Williams, who has been hampered with a stress fracture in her right leg since the Blue Devils’ NCAA Tournament games in March, sat out the first 10 minutes but finished with eight points and five rebounds in 11 minutes.
Freshman guard Alexis Jones started for Duke, scoring eight points with six assists.
NO. 6 KENTUCKY 80, HIGH POINT 45
In Lexington, Ky., A’dia Mathies scored all of her 17 points in the first half to help Kentucky rout High Point.
The Wildcats (2-1) recovered after a 85-51 loss Tuesday at No. 1 Baylor.
Cheyenne Parker finished with 13 points and 16 rebounds for the Panthers (1-2).
NO. 14 WEST VIRGINIA 75,
SOUTH CAROLINA UPSTATE 45
In Morgantown, W.Va., Bria Holmes scored a game-high 14 points off the bench to lead a balanced offense as West Virginia defeated South Carolina Upstate.
NO. 20 OHIO STATE 78, WINTHROP 53
In Columbus, Ohio, Darryce Moore and Tayler Hill scored 16 points apiece as Ohio State cruised to a win over Winthrop.
Ashley Adams added 14 points, six blocked shots and four assists for the Buckeyes (2-1), who have won 23 consecutive home games, the longest active streak in the Big Ten.
NO. 20 ST. JOHN’S 73, HOFSTRA 47
In New York, Nadirah McKenith scored 24 points while Shenneika Smith added 18 points and 15 rebounds to help St. John’s beat Hofstra.
Smith also had five assists for the Red Storm (2-1).