Lee caught 16 passes for a Pac-12-record 345 yards and two touchdowns to help USC (6-2, 4-2 Pac-12) build a 15-point lead midway through the third quarter.
But Scott led Arizona (5-3, 2-1) back, throwing for 369 yards and three touchdowns, including a 7-yarder to David Richards that put the Wildcats up 39-28 with just over 5 minutes left.
NO. 2 OREGON 70, COLORADO 14
In Eugene, Ore., Kenjon Barner rushed for 104 yards and two touchdowns, and Oregon easily took care of Colorado (1-7, 1-4 Pac-12) .
De’Anthony Thomas rushed for another score and added a 73-yard punt return for a touchdown before most of the Ducks’ offensive starters were pulled midway through the second quarter. Redshirt freshman quarterback Marcus Mariota passed for 136 yards and two TDs.
The Ducks (8-0, 5-0) built a 56-0 lead by halftime and their 70 points were the most they’d ever scored against a conference opponent.
NO. 9 OHIO STATE 35, PENN STATE 23
In State College, Pa., Braxton Miller ran for 134 yards and accounted for three touchdowns a week after getting knocked out of a game, leading No. 9 Ohio State past Penn State.
Ryan Shazier returned an interception 17 yards for a score early in the third quarter that gave the Buckeyes (9-0, 5-0 Big Ten) the lead for good, and the Nittany Lions (5-3, 3-1) had their five-game winning streak snapped.
KENT STATE 35, NO. 18 RUTGERS 23
In Piscataway, N.J., defensive end Mark Fackler returned his second interception 25 yards for a touchdown, and Kent State forced five other turnovers in stunning Rutgers for its biggest win since its first game in 1920.
The Golden Flashes (7-1) had been 0-22 against ranked teams, but they ended the best start for Rutgers (7-1) since the Scarlet Knights were 9-0
NO. 19 STANFORD 24, WASHINGTON STATE 17
In Stanford, Calif., Ed Reynolds returned an interception for a touchdown and No. 19 Stanford sacked Jeff Tuel 10 times to overcome a sloppy offensive effort in a victory over Washington State.
The Cardinal (6-2, 4-1 Pac 12) held the Cougars (2-6, 0-5) to minus-16 yards rushing.
NEBRASKA 23, NO. 20 MICHIGAN 9
In Lincoln, Neb., Ameer Abdullah ran for 101 yards and a touchdown and Nebraska (6-2, 3-1) took control of the Big Ten Legends Division by beating Michigan 5-3, 3-1) .
Wolverines quarterback Denard Robinson left the game late in the first half with a right elbow injury. Robinson, who spent the second half on the sideline in an overcoat, watched as freshman backup Russell Bellomy threw three interceptions.
The Huskers moved into a first-place tie with Michigan in the Legends but own the tiebreaker.
NO. 21 BOISE STATE 45, WYOMING 14
In Laramie, Wyo., D.J. Harper rushed for 105 yards and two touchdowns to lead Boise State to an easy victory over Wyoming for the Broncos’ seventh consescutive win.
Harper scored on runs of 12 and 3 yards, and Joe Southwick completed 20 of 28 passes for 198 yards and one interception for the Broncos (7-1, 4-0 Mountain West).
Wyoming (1-7, 0-4) was without head coach Dave Christensen, who was fined $50,000 and suspended by the school for the week over his conduct after a 28-27 loss to Air Force on Oct. 13.
MIAMI (OHIO) 23, NO. 23 OHIO 20
In Oxford, Ohio, instead of attempting a tying field goal, Ohio went for it, and Tyler Tettleton was sacked as time ran out, preserving Miami of Ohio’s upset over the Bobcats.
The Bobcats (7-1, 3-1 Mid-American Conference) played as a ranked team for the first time since 1968.