Miller rushed for 161 yards, a record for an Ohio State quarterback, and threw for two scores to lead the 18th-ranked Buckeyes to a 56-10 victory over Miami (Ohio).
Meyer, who won two national titles at Florida, is unbeaten in 11 season openers.
NO. 1 SOUTHERN CAL 49, HAWAII 10
In Los Angeles, Marqise Lee caught a 75-yard touchdown pass on the first play from scrimmage and returned a kickoff 100 yards for a score, and No. 1 Southern California rolled to a 49-10 victory over Hawaii on Saturday night.
Matt Barkley kicked off his Heisman Trophy campaign with 377 yards passing and four touchdowns.
NO. 11 WEST VIRGINIA 69, MARSHALL 34
In Morgantown, W.Va., Geno Smith threw for 323 yards and four touchdowns to lead West Virginia to its highest-scoring season opener in school history.
Smith completed 32 of 36 passes without an interception and set a school record for career completions before sitting out most of the fourth quarter.
NO. 15 TEXAS 37, WYOMING 17
In Austin, Texas, Joe Bergeron and Malcolm Brown both rushed for more than 100 yards and combined for three touchdowns, leading Texas.
Texas quarterback David Ash, who won the starting job over Case McCoy in training camp, was an efficient 20-of-27 passing for 156 yards and a touchdown to Jaxon Shipley.
NO. 12 WISCONSIN 26, NORTHERN IOWA 21
In Madison, Wis., Montee Ball rushed for 120 yards and a touchdown, and Wisconsin needed a tipped pass on a late fourth-and-1 play to survive a fourth-quarter scare from Northern Iowa.
NO. 17 NEBRASKA 49, SOUTHERN MISSISSIPPI 20
In Lincoln, Neb., Taylor Martinez threw for a career-high 354 yards and matched his high with five touchdown passes to lead Nebraska to a victory over Southern Mississippi.
NO. 19 OKLAHOMA STATE 84, SAVANNAH STATE 0
In Stillwater, Okla., freshman Wes Lunt completed all 11 of his passes in a brief first outing as the new starting quarterback for Oklahoma State and the defending Big 12 champions drove for touchdowns on their first five possessions in the rout.
Joseph Randle ran for 107 yards and two TDs.
NO. 22 KANSAS STATE 51, MISSOURI STATE 9
In Manhattan, Kan., Collin Klein threw for 169 yards and two touchdowns, John Hubert ran 95 yards for a fourth-quarter score and Kansas State pulled away late to knock off Missouri State.
Hubert finished with 152 yards rushing, Braden Wilson and Daniel Sams added touchdown runs, and Tramaine Thompson returned a punt 89 yards for another score as the Wildcats (1-0) tuned up for next week’s showdown with Miami with an impressive second-half scoring binge.
The game was tied 9-9 early in the third quarter before Kansas State piled up 42 straight points against the team picked to finish last in the Missouri Valley Conference.