Leading by five at the half, Georgia (18-6, 7-4 Southeastern Conference) scored two quick baskets to start the second half and the Lady Dogs never looked back.
The game was James’ first back after missing five in a row because of a right knee injury.
“It was great to see (James) out there moving around, doing the things that we like for her to do,” Georgia coach Andy Landers said. “Krista Donald is a play-maker. She can rebound the ball, she can make plays.”
Shafontaye Myers and Meghan Perkins scored 16 points each to led Alabama (10-14, 0-10).
NO. 2 NOTRE DAME 90, DEPAUL 70
In South Bend, Ind., Natalie Novosel scored 17 of her 21 points in the first half to help Notre Dame (23-1, 10-0 Big East) coast past DePaul (17-7, 5-5).
The Irish scored 56 points in the first half, shooting 72 percent from the field.
The win was the 20th in a row for Notre Dame matching the second longest streak in school history.
LOUISIANA STATE 61, NO. 6 KENTUCKY 51
In Baton Rouge, Adrienne Webb scored 16 of her 19 points in the second half and Louisiana State University (15-8, 5-5 SEC) snapped Kentucky’s 10-game winning streak.
LaSondra Barrett scored all of her 12 points in the final 20 minutes for the Lady Tigers, who came in having lost five of six games but rarely trailed as the Wildcats (21-3, 10-1) managed to shoot only 35 percent.
A’dia Mathies scored all of her 12 points in the second half to lead Kentucky.
NO. 7 MIAMI 68, CLEMSON 47
In Coral Gables, Fla., Shenise Johnson scored 19 points to lead Miami (20-3, 9-1 Atlantic Coast Conference) over Clemson (6-15, 2-8).
The Hurricanes broke the game open with a 17-1 run midway through the first half. Riquna Williams hit two 3-pointers and Johnson and Shawnice Wilson both scored five points during the run.
Nikki Dixon scored 16 points to lead Clemson, which has lost five of six.
NO. 8 TENNESSEE 82,
In Knoxville, Tenn., Glory Johnson had 14 points and 11 rebounds to help Tennessee (17-6, 8-2 SEC) beat Auburn (11-13, 3-8).
The Lady Vols turned 23 Auburn turnovers into 21 points and outshot the Tigers 50 percent to 37 percent in the second half.
NO. 12 DELAWARE 68, VIRGINIA COMMONWEALTH 49
In Newark, Del., Elena Delle Donne scored 22 points to lead four Delaware players in double figures and the Blue Hens (20-1, 11-0 Colonial Athletic Association) defeated Virginia Commonwealth (13-9, 6-5).
NO. 15 PURDUE 77, ILLINOIS 66
In West Lafayette, Ind., Sam Ostarello scored a career-high 21 points and matched her season-high with 13 rebounds to help Purdue (19-5, 9-2 Big Ten) remain on top of the Big Ten with a victory over Illinois (8-16, 2-9).
NO. 19 PENN STATE 68, MINNESOTA 65
In Minneapolis, Mia Nickson scored 20 points and Alex Bentley added 16 points, including the go-ahead 3-pointer with 38.9 seconds to play, to help Penn State (18-5, 8-3 Big Ten) rally past Minnesota (12-13, 4-7).
The Lady Lions (18-5, 8-3 Big Ten) trailed by 15 points in the first half and still trailed by three with 90 seconds remaining. But Penn State closed the game on an 8-2 run to secure its eighth win in its past 10 games.
NO. 25 TEXAS TECH 76, MISSOURI 49
In Lubbock, Texas, Casey Morris scored 15 points to lead four Texas Tech players in double figures and the Lady Raiders (16-6, 4-6 Big 12) beat Missouri (10-11, 0-10).