Georgia (6-1) scored the first 16 points of the game in the initial 7 minutes and never looked back.
Jasmine Hassell added 12 points for the Lady Dogs.
Tiara Knotts and Tracey Flowers led South Carolina State (2-3) with 10 points apiece.
NO. 1 BAYLOR 91, TEXAS SOUTHERN 39
In Waco, Texas, Brittney Griner had 23 points and 14 rebounds for her fifth double-double this season for top-ranked Baylor, which stretched its home winning streak to 27 games.
Odyssey Sims had 19 points, nine assists and a career-high eight steals while playing on 24 minutes for the Lady Bears (7-0).
NO. 2 CONNECTICUT 92, TOWSON 31
In Hartford, Conn., Bria Hartley had 24 points and five assists as Connecticut (7-0) routed Towson, the Huskies’ final tuneup before playing host to defending national champion Texas A&M next week.
NO. 6 MARYLAND 74, MICHIGAN 65
In College Park, Md., Alyssa Thomas scored 24 points, and Maryland (8-0) used a late surge to top previously unbeaten Michigan (7-1) in the Big Ten/ACC Challenge.
NO. 11 RUTGERS 71, TEMPLE 50
In Piscataway, N.J., April Sykes scored a season-high 19 points and Rutgers (7-0) shot its way past Temple.
Khadijah Rushdan added 16 while Monique Oliver had 15 for the Scarlet Knights.
NO. 16 PENN STATE 103, NO. 14 NORTH CAROLINA 84
In State College, Pa., Zhaque Gray scored 25 points and Penn State (6-1) snapped a three-game losing streak in the Big Ten/ACC Challenge by defeating North Carolina.
Brittany Roundtree led North Carolina (5-1) with 27 points.
NO. 17 OHIO STATE 78, FLORIDA STATE 75 (OT)
In Columbus, Ohio, Tayler Hill scored 31 points to lead Ohio State (6-0) past Florida State in overtime.
NO. 19 TEXAS TECH 85, TEXAS STATE 40
In Lubbock, Texas, Kierra Mallard scored 18 points, Shauntal Nobles had a double-double off the bench and Texas Tech (6-0) beat Texas State.
NO. 20 GEORGETOWN 70, COPPIN STATE 54
In Baltimore, Sugar Rodgers scored 26 points and had seven 3-point field goals in a first-half barrage that led Georgetown (6-2) over Coppin State.
NO. 25 VANDERBILT 83, AUSTIN PEAY 51
In Clarksville, Tenn., Christina Foggie had a career-high 25 points, leading Vanderbilt (7-0) over Austin Peay.
SOUTH CAROLINA 67, XAVIER 56
In Cincinnati, Markeshia Grant scored 18 points and Aleighsa Welch added 16 off the bench to lead South Carolina (6-1) past Xavier.
GEORGIA TECH 73, NEBRASKA 57
In Atlanta, Tyaunna Marshall had 28 points and pulled down 13 rebounds to lead Georgia Tech (5-2).