James had only 27 yards at halftime after being targeted by the Volunteers' defense for the entire first half. He started picking up momentum after the break, rushing for 25 yards on five carries in the Oregon's first second-half drive. He broke several tackles on the 72-yard touchdown run on the first play of the subsequent drive for the Ducks (2-0).
James returned to the field after serving his suspension for a offseason misdemeanor harassment charge.
Tennessee led 13-3 in the first half.
NO. 8 FLORIDA 38, SOUTH FLORIDA 14
In Gainesville, Fla., Jeff Demps ran for a career-high 139 yards and a touchdown, Justin Trattou returned an interception for a score and Florida beat South Florida.
The Gators (2-0) overcame a sluggish start for the second consecutive week, took advantage of five turnovers and extended their home winning streak to 13 games.
Big plays were key.
John Brantley's first TD pass came after an interception. Demps' 62-yard TD run followed a fumble. Mike Gillislee scored after another turnover. Trattou picked off a pass and rumbled 35 yards to the end zone. And the Gators turned Demps' 54-yard kickoff into a field goal.
Florida's first half included three punts and a missed field goal.
The Gators scored in the final minute of the half, then rolled after the intermission.
B.J. Daniels ran for 107 yards for the Bulls (1-1), but also threw four interceptions.
NO 14. ARKANSAS 31, LOUISIANA-MONROE 7
In Little Rock, Ark., Ryan Mallett completed nine of 11 passes in the third quarter, leading to a touchdown and a field goal, and Arkansas put away Louisiana Monroe after a sluggish first half.
Arkansas struggled to move the ball on offense and led only 7-0 at the halftime.
The Razorbacks defense smothered Louisiana-Monroe quarterback Kolton Browning, holding him to 2 of 9 passing and the team to 73 yards rushing through the third quarter.
NO. 19 LSU 27, VANDERBILT 3
In Nashville, Tenn., Stevan Ridley scored a 65-yard touchdown and ran for 144 of his 159 yards in the second half, and 19th-ranked LSU never trailed in defeating Vanderbilt.
It was the Tigers' seventh straight win in this series in the Southeastern Conference opener for both teams.
The Tigers came up with six sacks and held Vanderbilt to 135 yards total offense.
KENTUCKY 63, WESTERN KENTUCKY 28
In Lexington, Ky., Randall Cobb did it all, accounting for three touchdowns to lead Kentucky to a victory over Western Kentucky.
Quarterback Mike Hartline completed 16 of 20 passes for 213 yards and tied a career-high with three touchdowns.