He responded with a clutch performance at the foul line in the final minutes of regulation, and the Wildcats survived a scare from Robert Morris in a 73-70 overtime victory Thursday.
"I always think we're going to win; I always think we're going to find a way," coach Jay Wright said.
Trailing 55-47 with 4:19 left in the secon half, Reynolds attacked the basket and led a fearless rally from the free-throw line. His reliable stroke was absent, but he never stopped hustling in the second half, and Reynolds' sliding save of a loose ball at Robert Morris' end led to two free throws that cut the lead to 55-51.
The Colonials (23-12) coughed up the ball again. Reynolds was fouled again. And he delivered again on both attempts from the line and it was 55-53 with 2:10 left.
Robert Morris committed its 21st turnover and fouled Reynolds. Two more from the line and it was tied at 55 with 1:48 left in regulation.
All those missed jumpers -- Reynolds was 2 of 15 from the floor -- seemed forgotten for the Wildcats (25-7) .
"He is a live-by-the-sword, die-by-the-sword kind of guy," Wright said. "And I'll die by his sword any time because we've won so many. Even when he was missing them, I was saying, 'If that's how we're going to go down, I'll go down with him any time.' "
The Wildcats didn't going down.
SAINT MARY'S 80, RICHMOND 71
In Providence, R.I., Omar Samhan had 29 points and 12 rebounds despite spending most of the game in foul trouble, and Saint Mary's pulled away.
It was the first NCAA win for Saint Mary's in six tries since 1959. The 10th-seeded Gaels (27-5) will play Villanova on Saturday.
David Gonzalvez scored 18 and Kevin Anderson had 16 for Richmond (26-9).
OLD DOMINION 51, NOTRE DAME 50
In New Orleans, Carleton Scott's 3-pointer rattled out in the closing seconds, and 11th-seeded Old Dominion delivered the first upset of the tournament when it stunned sixth-seeded Notre Dame.
Frank Hassell scored 15 to lead Old Dominion (27-8), which had not won an NCAA Tournament game since beating Villanova in triple overtime in 1995 as a No. 14 seed.
Luke Harangody was held to four points for the Irish (23-12), all in the final minute, while Ben Hansbrough scored 17.
BAYLOR 68, SAM HOUSTON STATE 59
In New Orleans, Ekpe Udoh had 20 points and 13 rebounds, and Baylor won an NCAA Tournament game for the first time in 50 years.
Udoh also had five assists, two blocks and two steals for the third-seeded Bears (26-7), who broke open a close game down the stretch. Their first-round victory in the South Regional was their first in the tournament since beating BYU in 1950.
LaceDarius Dunn scored 13 points for Baylor.