The game will likely decide the Southeastern Conference East title and a trip to Atlanta for the Dec. 4 championship game.
South Carolina (6-2, 4-2 SEC) holds a one-game lead over Florida (5-3, 3-3) in the SEC East. The Gamecocks play host to Arkansas this week, while Florida plays at Vanderbilt.
Also on Nov. 13, Georgia will travel to undefeated Auburn and the longtime rivals will play at 3:30 p.m. on CBS-Ch. 12.