Firefighters were called about 4:30 a.m. to the building at 12th and Broad streets, where they found the third story on fire and a man trying to escape from a window on that floor. He was rescued without serious injuries.
Firefighters worked the fire for most of the day. The building contained Downtown Dental on the bottom floor and six apartments on the upper floors.
Fire Deputy Chief Sterling Jones said Monday that investigators had not yet determined the cause of the fire. Given the size of the building, he said, it could take several days to determine a point of origin.