Crystal Lynn Krentler, 35, was airlifted to the hospital in critical condition after her husband, Brian Allen Orzechowski, 36, crossed the center line on Washington Road and hit an oncoming vehicle.
Orzechowski was pronounced dead at the scene. Columbia County Coroner Vernon Collins said the couple were on their way to their honeymoon at Pointes West Army Resort at Thurmond Lake.
Torvoy Curry, 35, who was driving the other vehicle, was charged with driving on a suspended license and with an open container of alcohol. Police said Curry was not at fault in the crash.