According to the South Carolina Highway Patrol, the driver was traveling south on Old Barnwell Road on a 1972 Harley-Davidson when he went off the right side of the road at 10:50 p.m. and hit the tree.
Aiken County Coroner Tim Carlton said the driver, Jerry Siraud, of Matties Country Court, was pronounced dead at the scene.
Siraud was not wearing a helmet.
Toxicology results are pending.
His death was the 14th traffic fatality in Aiken County this year.