Aiken Department of Public Safety Capt. David Turno said Leon Jacob Simmons, 17; Reshawn Isaac, 21; Brian Morton, 18; and Markese Dequam East, 19, were charged with murder, armed robbery and first-degree burglary.
Aiken County Coroner Tim Carlton said Shane Jones, 19, was shot several times Tuesday at his home in Crosland Park neighborhood.
Turno said police were called to the home in the 1300 block of Aldrich Street about midnight.
Jones was dead when police arrived.
Authorities were later alerted to a woman at the hospital seeking treatment for gunshot wounds. She was treated and released.
Turno said investigators spent the morning speaking to several witnesses who left the scene after the shooting.
“This was not random,” he said. “This house was targeted.”