Officers from Richmond County and North Augusta Public Safety stood in front of a table littered with plastic bags of cocaine, cash and marijuana, along with firearms, as sheriff's Lt. Robert Partain announced the arrest of Marion Sturgis Donaldson, 34, of the 100 block of Oakland Avenue in North Augusta; and Dorsett Mandrell Williams, 29, of the 2300 block of Rutherford Drive in Augusta.
Both were charged with trafficking in cocaine.
Police seized about 3 1/2 kilograms of cocaine, which Partain said was valued at about $200,000.
Authorities also seized between $100,000 and $125,000 along with eight vehicles, including a Mercedes, a BMW, a motorcycle, a truck, and "classic vehicles," Partain said.
Sheriff's Sgt. Allan Rollins said about 5 pounds of marijuana was seized, with a street value of about $5,500.
Partain said neither suspect was armed at the time of the arrests.
Donaldson was arrested early Friday in Richmond County, and Williams was arrested Friday night in Beech Island.
The six-month investigation also involved the Drug Enforcement Agency, the FBI, the district attorney's office and the Augusta Judicial Circuit.
Partain said work on the case had been going on "aggressively" for the past 10 days and that many such operations exist locally.
"We will have some effect because we've destroyed one organization," Partain said. "But ... there are many (others) that are known and unknown working in this whole area and Carolina and Georgia."