The store at 4324 Washington Road in Evans will have 45 employees. Moss and his wife and business partner, Rosemary, are leasing the newly-constructed, 2,800-square-foot restaurant space.
Initially, the Mosses planned to open their first restaurant in Evans, but construction was delayed because of the economy, Moss said.
They plan to open two additional franchise locations in the area. They would like to open the fourth location within the next year in either south Augusta or Grovetown, he said.
The Mosses opened their first Five Guys restaurant in 2008 at 2805 Washington Road in Augusta and their second store in October 2010 at 1909 Whiskey Road in Aiken.