"It was no longer profitable for us to operate at this location," Eric Harkreader, a spokesman for the pharmacy chain, said of the store at 2745 Washington Road.
The store closed Friday, and patient prescriptions were transferred across the street to the Walgreens pharmacy at 2744 Washington Road, Harkreader said.
Patients were notified ahead of the closing and could pick up their prescriptions at Walgreens starting Saturday, he said.
The Rite Aid store will reopen Saturday, and all merchandise, excluding prescriptions, will be marked 50 percent off. The store will likely remain open for liquidation for several weeks, or until enough of the merchandise has been bought, Harkreader said.
The decision was made as part of routine reviews Rite Aid does for all of its stores. The lagging sales predated road work on Alexander Drive, which has blocked one of the store's entrances, the spokesman said.
"The road construction probably didn't help," he said.
Rite Aid still has eight other locations within 20 miles of the store.