Net income came to $425 million, or 50 cents a share, in the fourth quarter, compared with $19 million, or 2 cents a share, a year earlier.
Revenue rose 8 percent to $8.4 billion. Passenger revenue per available seat mile rose 12 percent.
Aircraft fuel expenses jumped 5 percent. Delta consumed less fuel in the quarter, but average fuel prices shot up about 20 percent.