Coroner Karl Addis says the wreck happened shortly after 10:30 p.m. Thursday near Seneca.
Addis says a pickup truck collided with the moped.
Addis says 17-year-old Adam George Ostrander Jr. of Seneca died at the scene.
Seventeen-year-old Charles’c Aviana Skelton of Seneca died about an hour later at the Oconee Medical Center Emergency Department.
Addis says neither teen was wearing a helmet. Autopsies are planned.