John Daniel Dean, 19, and Callee Smith, 12, were taken by ambulance to Medical College of Georgia Hospital.
They were hit by a northbound car driven by April Guin, 26, of Tignall. The accident occurred at 4:28 p.m. on Washington Road about five miles north of Thomson.
A Georgia State Patrol trooper, Rich Fishel, reported that Guin said she had looked down to check the time on her cellphone.
When she looked up again, she saw traffic stopped in the northbound lane.
To avoid hitting a car, she steered off the road to the right, striking the students as they started up a driveway.
The students's conditions were not known Friday night.